| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2153671 | Nuclear Medicine and Biology | 2013 | 12 Pages |
Abstract
We confirmed that both [11C]quinidine and [11C]laniquidar are P-glycoprotein substrates. At full P-gp blockade, tariquidar pre-treatment only demonstrated slight differences for [11C]quinidine between drug-resistant and drug-sensitive animals.
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![[11C]quinidine and [11C]laniquidar PET imaging in a chronic rodent epilepsy model: Impact of epilepsy and drug-responsiveness](/preview/png/2153671.png "First Page Preview: [11C]quinidine and [11C]laniquidar PET imaging in a chronic rodent epilepsy model: Impact of epilepsy and drug-responsiveness")
Authors
Stina Syvänen, Vera Russmann, Joost Verbeek, Jonas Eriksson, Maaike Labots, Christina Zellinger, Natalie Seeger, Robert Schuit, Marissa Rongen, Rolph van Kooij, Albert D. Windhorst, Adriaan A. Lammertsma, Elizabeth C. de Lange, Rob A. Voskuyl,