| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2154003 | Nuclear Medicine and Biology | 2010 | 7 Pages |
Abstract
It is demonstrated that with a B/I protocol the 11C-ABP688 distribution in late scans reflects the pattern of the total distribution volume and is therefore a measure for the density pattern of mGluR5. The early scans following injection are related to blood flow, although not in a fully quantitative manner. The advantage of the B/I protocol is that no arterial blood sampling is required, which is advantageous in clinical studies.
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Authors
Cyrill Burger, Alexandra Deschwanden, Simon Ametamey, Anass Johayem, Bruno Mancosu, Matthias Wyss, Gregor Hasler, Alfred Buck,