Article ID Journal Published Year Pages File Type
2154205 Nuclear Medicine and Biology 2010 10 Pages PDF
Abstract
[125I]FlipADAM (1c) exhibited faster clearance from the brain and time to binding equilibrium when compared to [125I]2-(2′-((dimethylamino)methyl)-phenylthio)-5-iodophenylamine [125I]ADAM (1b) and a higher target to non-target ratio when compared to [125I]5-iodo-2-(2′-((dimethylamino)methyl)-phenylthio)benzyl alcohol [125I]IDAM (1a). Therefore, [123I]FlipADAM (1c) may be an improved SPECT tracer for imaging SERT.
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