Article ID Journal Published Year Pages File Type
2154227 Nuclear Medicine and Biology 2011 8 Pages PDF
Abstract
Initial rates of FLT uptake were a function of both concentrative and equilibrative transporters. TK1 activity was an absolute requirement for the accumulation of FLT. Retention was dependent on nucleoside/nucleotide efflux and retrograde metabolism of FLT nucleotides.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Preview
The role of nucleoside/nucleotide transport and metabolism in the uptake and retention of 3′-fluoro-3′-deoxythymidine in human B-lymphoblast cells
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