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Syntheses and biological activities of novel 2-methoxyestradiol analogs, 2-fluoroethoxyestradiol and 2-fluoropropanoxyestradiol, and a radiosynthesis of 2-[18F]fluoroethoxyestradiol for positron emission tomography

Article ID Journal Published Year Pages File Type
2154355 Nuclear Medicine and Biology 2008 8 Pages PDF
Abstract
2FEE2 and 2FPE2 showed similar activity as 2ME2. 2[18F]FEE2 was synthesized to be utilized as a PET radiotracer to measure the biological efficacy of 2ME2 and its analogs in vivo.
Keywords
2-MethoxyestradiolPET
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Preview
Syntheses and biological activities of novel 2-methoxyestradiol analogs, 2-fluoroethoxyestradiol and 2-fluoropropanoxyestradiol, and a radiosynthesis of 2-[18F]fluoroethoxyestradiol for positron emission tomography
Authors
Jiyoung Mun, Yuefang Wang, Ronald J. Voll, Daniel Escuin-Borras, Paraskevi Giannakakou, Mark M. Goodman,
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Journal
Nuclear Medicine and Biology
Journal: Nuclear Medicine and Biology
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