| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2154365 | Nuclear Medicine and Biology | 2008 | 12 Pages |
Abstract
Small structural variations on the TZTP structure greatly altered the PK in brain and behavior in blood with little change in the log D, PPB or affinity. The study suggests that 11C-radiolabeled 3 will be a suitable alternative to [18F]FP-TZTP for translational studies in humans.
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Authors
Alicia E. Reid, Yu-Shin Ding, William C. Eckelman, Jean Logan, David Alexoff, Colleen Shea, Youwen Xu, Joanna S. Fowler,