| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2154526 | Nuclear Medicine and Biology | 2009 | 11 Pages |
Abstract
The 64Cu-NO2A-8-Aoc-BBN(7-14)NH2 produced high-quality microPET images. The pharmacokinetic profile justifies investigation of this bioconjugate as a potentially useful diagnostic/therapeutic agent. Additionally, the bioconjugate would serve as a good starting point for modification and optimization of similar agents to maximize tumor uptake and minimize nontarget accumulation.
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![In vitro and in vivo analysis of [64Cu-NO2A-8-Aoc-BBN(7-14)NH2]: a site-directed radiopharmaceutical for positron-emission tomography imaging of T-47D human breast cancer tumors](/preview/png/2154526.png "First Page Preview: In vitro and in vivo analysis of [64Cu-NO2A-8-Aoc-BBN(7-14)NH2]: a site-directed radiopharmaceutical for positron-emission tomography imaging of T-47D human breast cancer tumors")
Authors
Adam F. Prasanphanich, Lauren Retzloff, Stephanie R. Lane, Prasant K. Nanda, Gary L. Sieckman, Tammy L. Rold, Lixin Ma, Said D. Figueroa, Samantha V. Sublett, Timothy J. Hoffman, Charles J. Smith,