Article ID Journal Published Year Pages File Type
2154551 Nuclear Medicine and Biology 2010 5 Pages PDF
Abstract

Both mutant p53 and chemoresistance are poor prognostic factors in cancer. Many studies have examined the influence of these factors on fluoro-2-deoxy-d-glucose (FDG) incorporation. Whilst mutant p53 is associated with increased FDG incorporation, chemoresistance, especially when associated with P-glycoprotein, is associated with decreased FDG incorporation.

Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
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