Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2154551 | Nuclear Medicine and Biology | 2010 | 5 Pages |
Abstract
Both mutant p53 and chemoresistance are poor prognostic factors in cancer. Many studies have examined the influence of these factors on fluoro-2-deoxy-d-glucose (FDG) incorporation. Whilst mutant p53 is associated with increased FDG incorporation, chemoresistance, especially when associated with P-glycoprotein, is associated with decreased FDG incorporation.
Keywords
Related Topics
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Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Tim A.D. Smith,