| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2154792 | Nuclear Medicine and Biology | 2006 | 9 Pages |
Abstract
This study is part of our first look at a novel class of nonsteroidal AR antagonists as positron emission tomography (PET) imaging agents, which are alternatives to steroidal AR agonist-based imaging agents. Although 76Br-3 has a significant affinity for ARs, it showed limited promise as a PET imaging agent because of its poor target-tissue distribution properties.
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![Synthesis and biological evaluation of a nonsteroidal bromine-76-labeled androgen receptor ligand 3-[76Br]bromo-hydroxyflutamide](/preview/png/2154792.png "First Page Preview: Synthesis and biological evaluation of a nonsteroidal bromine-76-labeled androgen receptor ligand 3-[76Br]bromo-hydroxyflutamide")
Authors
Ephraim E. Parent, Carl Jenks, Terry Sharp, Michael J. Welch, John A. Katzenellenbogen,