| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2154889 | Nuclear Medicine and Biology | 2007 | 9 Pages |
Abstract
The biodistribution and blood clot uptake of 99mTc-NC100668 and [Asn-U-14C]NC100668 are similar. With the exception of the kidneys, 99mTc-NC100668 biodistribution and blood clot uptake are unaffected by the presence of unlabelled NC100668. The kidney retention of radioactivity is probably due to transglutaminase activity and, to a lesser extent, nonspecific charge-mediated endocytosis.
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Authors
David Edwards, Joanne Lewis, Mark Battle, Rochelle Lear, Gill Farrar, David J. Barnett, Vanessa Godden, Catherine Edwards, Alexandra Oliveira, HÃ¥kan Ahlström,