Article ID Journal Published Year Pages File Type
2154904 Nuclear Medicine and Biology 2008 6 Pages PDF
Abstract
Gemcitabine pretreatment up-regulates sstr expression and acts as a radiosensitizer through cell cycle modulation. The rational combination of gemcitabine and sstr-targeted radiopharmaceuticals represents a promising chemoradiation therapeutic tool with great potential to improve clinical outcomes and, thus, merits further study.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Preview
Enhancement of somatostatin-receptor-targeted 177Lu-[DOTA0-Tyr3]-octreotide therapy by gemcitabine pretreatment-mediated receptor uptake, up-regulation and cell cycle modulation
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