Article ID Journal Published Year Pages File Type
2155100 Pathology - Research and Practice 2015 9 Pages PDF
Abstract
This study demonstrates that deregulation of Wnt/β-catenin-signaling and high-grade expression of cancer stem cell markers correlate with metastasis to the liver, but not to the CNS. These data implicate that in CRC other mechanisms than deregulation of Wnt/β-catenin-signaling and acquisition of cancer stemness are required for formation of CNS metastasis.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Preview
Expression of cancer stem cell markers in metastatic colorectal cancer correlates with liver metastasis, but not with metastasis to the central nervous system
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