| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2155178 | Pathology - Research and Practice | 2015 | 5 Pages |
Abstract
Tyrosine kinase receptors showed a distinct expression pattern in soft tissue sarcomas. High expression of VEGFR2 (KDR) is significantly associated with decreased patients' survival. High VEGFR 1-3 and PDGFRB are significantly correlated with higher tumor grading. Protein signatures might be evaluated before targeted therapy to give a rationale for an eligible personalized therapy.
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Authors
Eric Kampmann, Annelore Altendorf-Hofmann, Sebastian Gibis, Lars H. Lindner, Rolf Issels, Thomas Kirchner, Thomas Knösel,