Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2155460 | Pathology - Research and Practice | 2014 | 9 Pages |
Abstract
Our results suggest a pathophysiological role of TRAIL in both, HCV infection and therapy. Further studies need to elaborate possible TRAIL-related targets for clinical applications.
Keywords
pLADTRAIL-R2TRAIL-R1cFLIPRBVPEG-IFNFADDEVRTRAIL-R3TNFRVRSVRmIgGNF-κBcEVRHCCMouse IgGEBVinterferonpegylated interferon alphaIFNApoptosisRibavirincytomegalovirusCMVtumor necrosis factornuclear factor kappa BTRAILTNF-related apoptosis inducing ligandHepatitis CEpstein–Barr virusearly virologic responserapid virologic responseSustained virologic responseHepatocellular carcinomaCaspase-8death receptor
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Authors
Sylvia Brost, Anna Zimmermann, Ronald Koschny, Jaromir Sykora, Wolfgang Stremmel, Peter Schirmacher, Henning Walczak, Tom M. Ganten,