| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2158913 | Radiotherapy and Oncology | 2009 | 6 Pages |
Abstract
Cetuximab binds to EGFRvIII and leads to the initial activation, internalization and subsequent downregulation of EGFRvIII, but it does not seem to modulate the proliferation or radiosensitivity of EGFRvIII-expressing glioma cells. Thus, approaches to treat EGFRvIII-expressing glioma cells should be evaluated more carefully.
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Authors
Barry Jutten, Ludwig Dubois, Younan Li, Hugo Aerts, Bradly G. Wouters, Philippe Lambin, Jan Theys, Guido Lammering,