| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2159154 | Radiotherapy and Oncology | 2010 | 5 Pages |
PurposeBesides sparing the parotid gland, sparing the submandibular gland is considered to be important in preventing xerostomia in head-and-neck cancer patients. Delineation of the submandibular gland at CT, and even on T1T1- and T2T2-weighted MR images, is difficult, due to low contrast with the surrounding tissues. MR sialography might be used for delineation.Methods and materialsSixteen oropharyngeal cancer patients received a CT and MRI exam as part of the standard treatment imaging protocol. Patients were scanned in their five-point RT immobilization mask. The MRI exam included T1T1- and T2T2-weighted MRI scans and an MR sialography scan. Thirty submandibular glands were delineated on only CT, on the combined CT and T1T1- and T2T2-weighted MRI scans and on all MR images. A Wilcoxon signed-rank test was performed to test if the delineated volumes were significantly different.ResultsThe delineated volume of the submandibular gland was 7.3 mL in the CT-delineation, 7.1 mL in the CT/MRI-delineation and 8.1 mL in the MRI-delineation. The MRI-delineation was significantly larger than the other delineations (p < 0.001). The differences were mainly located in the cranial direction.ConclusionThe delineation of the submandibular gland was improved in the cranial direction by using T1T1- and T2T2-weighted MRI and MR sialography, compared to the other delineations.
