Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2161520 | Radiotherapy and Oncology | 2006 | 8 Pages |
Abstract
The protection produced when Eukarion-189 was given shortly after irradiation suggests that DNA damage observed in the lung may be caused by chronic production of ROS induced by a chronic inflammatory response initiated by the radiation treatment. We speculate that our failure to observe protection against severe morbidity at 2-3 months may be because our treatment regime only blocked the initial wave of ROS production and that treatment needs to be more prolonged to suppress the effects of a chronic inflammatory response.
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Authors
Aimée R. Langan, Mohammed A. Khan, Ivan W.T. Yeung, Jake Van Dyk, Richard P. Hill,