Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2162211 | Seminars in Oncology | 2012 | 8 Pages |
Abstract
Sipuleucel-T is an autologous cellular immunotherapy designed to stimulate an immune response to prostate cancer that prolongs the overall survival of men with asymptomatic or minimally symptomatic metastatic castrate-resistant prostate cancer (CRPC). The clinical development program and key efficacy, safety, and immune response findings from the phase III studies are presented. The integration of sipuleucel-T into the treatment paradigm of advanced prostate cancer and future directions for research are discussed.
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Authors
Mark W. Frohlich,