Article ID Journal Published Year Pages File Type
2162959 Seminars in Oncology 2008 9 Pages PDF
Abstract
Peritoneal carcinomatosis (the implantation of tumor cells throughout the peritoneal cavity) occurs in as many as 50% of patients with colorectal cancer and in up to 25% is the only site of recurrence. There is increasing evidence that aggressive debulking of peritoneal only disease followed by intraperitoneal chemotherapy can have significant impact on the patient's quality and sometimes quantity of life. This chapter will provide an overview of the biologic basis of pathogenesis and the treatment of peritoneal metastases from colorectal cancer.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
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