Article ID Journal Published Year Pages File Type
2165907 Cell Calcium 2015 10 Pages PDF
Abstract

- ClC-5 is an endosomal Cl−/H+ antiporter of the CLC family of ion channels and transporters.
- ClC-5 is critical for proper endocytosis.
- Mutations in ClC-5 cause Dent's disease.
- The physiological role of ClC-5 in endosomes is still unclear.
- ClC-5 has very peculiar biophysical properties.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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