Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2165907 | Cell Calcium | 2015 | 10 Pages |
Abstract
- ClC-5 is an endosomal Clâ/H+ antiporter of the CLC family of ion channels and transporters.
- ClC-5 is critical for proper endocytosis.
- Mutations in ClC-5 cause Dent's disease.
- The physiological role of ClC-5 in endosomes is still unclear.
- ClC-5 has very peculiar biophysical properties.
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Authors
Michael Pusch, Giovanni Zifarelli,