| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2166159 | Cell Calcium | 2011 | 9 Pages |
Abstract
⺠ORAI channels reconstitute the major calcium entry pathway in T cells. ⺠Different calcium signals are translated into different T cell functions. ⺠Calcium dependent proliferation, apoptosis and tolerance define the immune response.
Keywords
DISCstore-operated Ca2+STIMCa2+ release-activated Ca2+ channelLPLTregCRACCREBIP3RAICDAPCGALTIBDMEF2NFATTCr[Ca2+]iOraiantigen-presenting cellgut-associated lymphoid tissueInflammatory bowel diseaseProliferationToleranceautoimmune regulatorApoptosisRegulatory T cellT cellSOCNuclear Factor of Activated T Cellsintracellular Ca2+ concentrationactivation induced cell deathlamina propria lymphocytesLymphocytemajor histocompatibility complexMHCAIREdeath-inducing signaling complexCRAC channelCalcium channelCalciumIP3 receptorT cell receptors
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Authors
Bin Qu, Dalia Al-Ansary, Carsten Kummerow, Markus Hoth, Eva C. Schwarz,