Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2166733 | Cell Calcium | 2006 | 8 Pages |
Abstract
T-type, or low-voltage-activated (LVA), tiny and transient Ca2+ currents pare more and more recognised as universal players in a plethora of cell functions and are also more and more connected to several diseases. This short introduction reviews the discovery of T-type Ca2+ channels, describes its basic properties and sketches its cloning and physiological impact. Finally, an overview is given how research on T-type Ca2+ channels has developed in the last years and in which topics it is branching out, a process, which is still ongoing.
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Authors
Bernd Nilius, Karel Talavera, Alexei Verkhratsky,