Article ID Journal Published Year Pages File Type
2167143 Cellular Immunology 2013 9 Pages PDF
Abstract
► Murine splenic keratin-reactive B cells express germline encoded VH and VK genes. ► BCRs on murine keratin-reactive B cells frequently utilize DFL16.2 and JK2 in CDR3 regions. ► Keratin-reactive B cells have antigen-presentation capacities. ► Keratin-reactive B cells are ineffective in activating T cells from lymph nodes. ► Low B7-1/2 may underlie incomplete role of keratin-reactive B cell presentation.
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