| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2169850 | Current Opinion in Cell Biology | 2012 | 8 Pages |
Abstract
Polarity within lymphocytes has been recognized to regulate a variety of processes, including migration, signaling, and the execution of effector function. It has been recently proposed, however, that this polarized behavior may also serve a different purpose in lymphocytes that have not yet encountered their foreign antigen - to coordinate asymmetric cell division. Asymmetric division is an evolutionarily conserved mechanism allowing a single cell to give rise to two distinct daughter cells from inception. In this review, recent findings in polarity and asymmetric division in lymphocytes are discussed.
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Authors
John T Chang,