Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2169865 | Current Opinion in Cell Biology | 2013 | 7 Pages |
Abstract
Recent work revealed that cullin-RING ligases and the anaphase-promoting complex, two classes of ubiquitin ligases that are essential for cell division in all eukaryotes, are regulated in a highly dynamic manner. Here, we describe mechanisms that establish the dynamic regulation of these crucial ubiquitylation enzymes and discuss the functional consequences for cell division control.
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Authors
Allison Craney, Michael Rape,