| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2169993 | Current Opinion in Cell Biology | 2010 | 7 Pages |
Abstract
Many different signals for cell death converge on outer mitochondrial membrane permeabilization, a process controlled by the Bcl-2 family of proteins. Recent structural and biochemical analyses emphasize that key regulatory interactions between different classes of Bcl-2 family members occur at and in intracellular membranes, and insertion into membranes causes functionally important conformational changes in the proteins.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Christian Bogner, Brian Leber, David W Andrews,