Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2170296 | Current Opinion in Cell Biology | 2007 | 5 Pages |
Abstract
Despite considerable efforts, the spatial link between the nuclear architecture and the genome remains enigmatic. The 4C method, independently innovated in four different laboratories, might in combination with other methods change that. As this method is based on the unbiased identification of sequences interacting with specific baits, there are unique opportunities for unravelling the secrets of how the genome functions in 3D.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Rolf Ohlsson, Anita Göndör,