Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2170330 | Current Opinion in Cell Biology | 2006 | 8 Pages |
Abstract
Unlike most somatic cells, leukocytes are constitutively non-adherent. However, adhesive interactions are not only a required step in essentially all effector functions performed by leukocytes, but they also relay increasingly well-defined intracellular signals that affect the leukocyte as well as the surrounding tissues. Dissecting such signals in leukocytes has provided a wealth of information that contributes to our understanding of how adhesion controls higher-order biological responses, ranging from cell migration to proliferation, differentiation and survival.
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Authors
Raffaella Molteni, Monica Fabbri, Jeffrey R Bender, Ruggero Pardi,