Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2170372 | Current Opinion in Cell Biology | 2006 | 8 Pages |
Abstract
The packaging of DNA into chromatin creates a number of significant barriers to the detection of DNA lesions and their timely and accurate repair. Eukaryotic cells have evolved a number of enzymes that modulate chromatin structure and facilitate DNA repair. Recent research illustrates how nucleosome remodelling enzymes cooperate with both DNA-damage-inducible and constitutive histone modifications to promote many facets of the cellular response to DNA damage.
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Authors
Hugo Wurtele, Alain Verreault,