Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2172409 | Cytotherapy | 2006 | 11 Pages |
Abstract
This bulk culture method is simple and reliable for expanding human Ag-specific T cells using peptide-pulsed K562-A*0201 cells. This HLA-matched APC line can be adapted to other HLA haplotypes, and has advantages for monitoring clinical trials of immunotherapy with limited availability of autologous APC and PBMC from patients.
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Authors
J. Yuan, H.F. Gallardo, T. Rasalan, R. Ranganathan, J. Wang, Y. Zhang, K. Panageas, R. Stan, J.W. Young, A.N. Houghton, J.D. Wolchok,