| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2172422 | Cytotherapy | 2008 | 10 Pages |
Abstract
Plt did not negatively influence DC maturation but enhanced the expression of co-stimulatory molecules and the release of IL-12. Functionally this was reflected by a strong T-cell response that involved T-helper 1 (Th1)- as well as Th2-biased T cells. Our findings show that controlling the Plt concentration may provide important advantages for the generation of DC for use in immunotherapy.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
X.D. (Dr med), J. Müller-Berghaus, T. Kälsch, D. Schadendorf, M. Borggrefe, H. Klüter,