Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2173072 | Developmental Biology | 2013 | 12 Pages |
Abstract
⺠Ccm2l is a novel protein with identity to Ccm2. ⺠ccm2l is essential for normal cardiovascular development in zebrafish. ⺠ccm2l is an enhancer of the Heg-CCM dilated heart phenotype. ⺠Overexpression of ccm2 partially rescues ccm2l morphant defects. ⺠Ccm2l binds Ccm1 in an interaction that requires Ccm1's NPXY/F motifs.
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Authors
Jonathan N. Rosen, Vanessa M. Sogah, Lillian Y. Ye, John D. Mably,