| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2173242 | Developmental Biology | 2012 | 12 Pages |
Abstract
⺠We examine the process of cyst stem cell (CySC) development in Drosophila testes. ⺠CySC establishment correlates with formation of the testis stem cell niche. ⺠Jak-STAT signaling is necessary and sufficient for CySC maintenance in larval testes. ⺠Zygotic Stat92E is not required for the initial establishment of CySCs at the embryo-larval transition. ⺠Signaling from CySCs promotes the maintenance of germline stem cells (GSCs) in larval testes.
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Authors
D. Sinden, M. Badgett, J. Fry, T. Jones, R. Palmen, X. Sheng, A. Simmons, E. Matunis, M. Wawersik,