Article ID Journal Published Year Pages File Type
2173399 Developmental Biology 2012 13 Pages PDF
Abstract
► Zebrafish eomesa mutation was recovered by TILLING. ► Maternal Eomesa is required for the timely initiation of epiboly but is not required for epiboly progression. ► Yolk cell microtubules are defective in maternal-zygotic eomesa mutant embryos at dome stage but recover by 75% epiboly. ► Deep cell morphology is altered in maternal-zygotic mutant embryos. ► Expression the endoderm markers sox32, bon and og9x is abnormal in maternal-zygotic eomesa mutant embryos.
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