| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2173457 | Developmental Biology | 2011 | 13 Pages |
Abstract
⺠The Type III TGFβ Receptor is required for coronary vessel development. ⺠Null epicardial cells have decreased proliferation and invasion. ⺠Cells lose responsiveness to TGFβ, FGF-2, and Hyaluronic Acid. ⺠Invasion requires a domain in the receptor and the scaffolding protein, GIPC. ⺠Type III Receptor regulates vessel formation by a unique pathway.
Keywords
Smooth Muscle Alpha ActinGFPGIPCTGFβFGFTGFBR1PDGFFGFRIGF-IRWT-1ZO-1PDGFRTGFβR2SM22αEpicardiumtransforming growth factor-betaTUNELCoronary vesselsVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)platelet-derived growth factorfibroblast growth factorgreen fluorescent proteinplatelet-derived growth factor receptorfibroblast growth factor receptor
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Authors
Nora S. Sánchez, Cynthia R. Hill, Joseph D. Love, Jonathan H. Soslow, Evisabel Craig, Anita F. Austin, Christopher B. Brown, Andras Czirok, Todd D. Camenisch, Joey V. Barnett,