Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2173558 | Developmental Biology | 2011 | 15 Pages |
Abstract
⺠Systemic loss of Pax3 results in pulmonary atresia and abnormal remodeling of aortic arch arteries. ⺠Wnt1-cre mediated Pax3 deletion in mouse embryos does not cause heart defects. ⺠Wnt1-cre mediated neural crest genetic ablation results in conotruncal heart defects. ⺠Pax3 functions in early neural crest progenitor specification and formation.
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Authors
Michael Olaopa, Hong-ming Zhou, Paige Snider, Jian Wang, Robert J. Schwartz, Anne M. Moon, Simon J. Conway,