Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2173763 | Developmental Biology | 2011 | 12 Pages |
Abstract
⺠Vascular ablation of Id genes circumvents embryonic lethality. ⺠Mice develop postnatal cardiac phenotypes.⺠Expression patterns of vascular/fibrotic/hypertrophic markers are altered. ⺠IGFbp3 reverses vascular markers, like angiopoietin1 and thrombospondin1/4. ⺠IGFbp3 reverses fibrotic, but not hypertrophic markers.
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Authors
Qingshi Zhao, Amanda J. Beck, Joseph M. Vitale, Joel S. Schneider, Shumin Gao, Corey Chang, Genie Elson, Samuel J. Leibovich, Ji Yeon Park, Bin Tian, Hyung-song Nam, Diego Fraidenraich,