Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2176137 | Developmental Biology | 2006 | 13 Pages |
Abstract
The atrioventricular heart valve leaflets and chordae tendineae are composed of diverse cell lineages and highly organized extracellular matrices that share characteristics with cartilage and tendon cell types in the limb buds and somites. During embryonic chicken valvulogenesis, aggrecan and sox9, characteristic of cartilage cells, are observed in the AV valve leaflets, in contrast to tendon-associated genes scleraxis and tenascin, present in the chordae tendineae. In the limb buds and
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Authors
Joy Lincoln, Christina M. Alfieri, Katherine E. Yutzey,