Identification of a permease gene involved in lactose utilisation in Aspergillus nidulans

Article ID	Journal	Published Year	Pages	File Type
2180940	Fungal Genetics and Biology	2012	11 Pages	PDF

Abstract

âº Identification beta-galactosidase/lactose permease gene cluster in Aspergillus nidulans. âº Cluster subject to CreA-independent carbon catabolite repression. âº MFS gene encodes physiological lactose uptake system of higher affinity. âº beta-Galactosidase gene is dispensable for lactose utilisation. âº Phylogenetics suggest cluster is ancient in ascomycetes.

Keywords

DCW RT-PCR MFS X-Gal lactose permease 5-bromo-4-chloro-3-indolyl-β-d-galactoside ortho-nitrophenyl-β-d-galactopyranoside disintegrations per minute Regulation of transcription Gene cluster Reverse transcriptase-polymerase chain reaction

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology

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Identification of a permease gene involved in lactose utilisation in Aspergillus nidulans

Authors

Erzsébet Fekete, Levente Karaffa, Bernhard Seiboth, Ãva Fekete, Christian P. Kubicek, Michel Flipphi,