| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2180953 | Fungal Genetics and Biology | 2012 | 11 Pages |
Abstract
⺠Gliotoxin exposure induces proteome remodelling in Aspergillus fumigatus. ⺠Intracellular glutathione facilitates gliotoxin sensitivity, via ROS formation. ⺠Gliotoxin exhibits potent antifungal effects. ⺠Gliotoxin resistance facilitates detection of targeted gene deletion. ⺠Gliotoxin may be part of the oxidant defense system in A. fumigatus.
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Authors
Stephen Carberry, Emer Molloy, Stephen Hammel, Grainne O'Keeffe, Gary W. Jones, Kevin Kavanagh, Sean Doyle,