| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2181280 | Fungal Genetics and Biology | 2008 | 6 Pages |
Abstract
Global transcriptional analysis of Candida albicans exposed to elevated ambient CO2 revealed a statistically significant differential regulation of 14 genes. Subsequent RNA hybridisation analysis of one gene, HSP12, confirmed CO2-regulation via a cAMP-dependent mechanism. Additionally, Northern analyses and gel mobility shift assays demonstrate the co-regulation of HSP12 by environmental pH via a Rim101-dependent mechanism.
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Authors
Chirag C. Sheth, Estelle G. Mogensen, Man Shun Fu, Ian C. Blomfield, Fritz A. Mühlschlegel,