Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2181689 | Fungal Genetics and Biology | 2007 | 4 Pages |
Abstract
Using techniques developed to study melanization in other fungi, we demonstrate that Coccidioides posadasii arthroconidia, spherules, and endospores produce melanin or melanin-like compounds in vitro and tissue forms synthesize pigment in vivo. Since melanin is an important virulence factor in other pathogenic fungi, it may affect the pathogenesis of coccidioidomycosis.
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Authors
Joshua D. Nosanchuk, Jieh-Juen Yu, Chiung-Yu Hung, Arturo Casadevall, Garry T. Cole,