| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2181951 | Gene Expression Patterns | 2013 | 9 Pages |
The expression of the chicken delta-protocadherin (Pcdh) subfamily was investigated in the developing feather buds of the chicken. The expression profiles of the eight investigated Pcdhs in the cells and tissues of the feather buds differ from each other. Pcdh1, Pcdh7, Pcdh8 and Pcdh10 are differentially expressed in the epidermis of the feather bud. Expression of Pcdh1 and Pcdh10 is restricted to the periderm and Pcdh17 expression to the epidermis of interbud region. Pcdh19 is mostly expressed at the anterior side of epidermis as well as in the blood vessels of the feather buds. Furthermore, Pcdh9 and Pcdh18 both are regionally expressed in the dermis of the feather bud. These results suggest that Pcdhs may play a variety of roles during avian feather bud formation.
► Eight delta-protocadherins are expressed during feather bud formation in chicken embryo. ► Each of the protocadherins exhibits a distinct spatiotemporal expression profile. ► Pcdh1, 7, 8, 10, 17, 19 are detected in the epidermis, while Pcdh1, 9, 18 in the dermis. ► Expression of Pcdh9 and Pcdh18 reflects the polarity of the feather buds. ► Delta-protocadherins may play a variety of roles during avian feather bud formation.
