Fabrication of cuprous oxide nanoparticles-graphene nanocomposite for determination of acetaminophen

A glassy carbon electrode modified with cuprous oxide nanoparticles-graphene composite film (Cu2O/GR) was prepared and applied to detect acetaminophen (AC). Scanning electron microscopy, energy dispersive X-ray spectroscopy and electrochemical impedance spectroscopy were applied for characterization of the proposed electrode. Cyclic voltammetry and square wave voltammetry were used to investigate the electrocatalysis oxidation of AC on Cu2O/GR. The linearity ranged from 2.0 × 10− 8 to 1.3 × 10− 6 M with a detection limit of 6.67 × 10− 9 M (S/N = 3) and the calculated sensitivity of 14,397.7 μA mM− 1 cm− 2. Under optimal conditions, the sensor displays good stability and satisfactory results in real samples analysis.

Graphical abstractAn electrochemical sensor based on cuprous oxide nanoparticles-graphene composite film (Cu2O/GR) modified glassy carbon electrode for detecting acetaminophen (AC) was fabricated by electro-deposition.Figure optionsDownload full-size imageDownload as PowerPoint slide