| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2182440 | Gene Expression Patterns | 2006 | 5 Pages |
Abstract
The nodal and nodal-related genes play fundamental roles during deuterostome left–right axis formation. Several of these genes show left-sided expression in the lateral plate mesoderm and brain region. We have isolated the nodal-related gene, CyNodal, from Cynops pyrrhogaster. CyNodal mRNA is detected at the marginal zone and left side of several tissues. The left-sideness of CyNodal mRNA expression is highly conserved throughout vertebrate evolution. However, CyNodal mRNA expression shows little variation from the Xenopus nodal-related gene 1, in that CyNodal gene expression in the left lateral plate mesoderm shifts from posterior to anterior at least twice.
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Authors
Yuzuru Ito, Tsutomu Oinuma, Kazuhiro Takano, Shinji Komazaki, Shuichi Obata, Makoto Asashima,