Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2187281 | Journal of Molecular Biology | 2008 | 8 Pages |
Abstract
Nucleotide incorporation during transcription by RNA polymerase is accompanied by pyrophosphate formation. Rapid release of pyrophosphate from the elongation complex at a rate consistent with productive transcription elongation occurs only in the presence of the correct next nucleotide for incorporation into the transcript.
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Authors
Ronald S. Johnson, Mark Strausbauch, Ryan Cooper, J. Kristen Register,