Article ID Journal Published Year Pages File Type
2187281 Journal of Molecular Biology 2008 8 Pages PDF
Abstract

Nucleotide incorporation during transcription by RNA polymerase is accompanied by pyrophosphate formation. Rapid release of pyrophosphate from the elongation complex at a rate consistent with productive transcription elongation occurs only in the presence of the correct next nucleotide for incorporation into the transcript.

Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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