Article ID Journal Published Year Pages File Type
2190681 Journal of Molecular and Cellular Cardiology 2012 10 Pages PDF
Abstract
► NE induces spontaneous activity in isolated PV cardiomyocytes. ► Morphological and electrophysiological properties differ between PV and LA myocytes. ► Both a1 and b1-receptor stimulations are required for NE-induced automaticity. ► Release of Ca2 + via IP3R activates NCX to cause automaticity. ► T-tubule system is enriched in PV cardiomyocytes, in contrast to atrial cells.
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