Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2190681 | Journal of Molecular and Cellular Cardiology | 2012 | 10 Pages |
Abstract
⺠NE induces spontaneous activity in isolated PV cardiomyocytes. ⺠Morphological and electrophysiological properties differ between PV and LA myocytes. ⺠Both a1 and b1-receptor stimulations are required for NE-induced automaticity. ⺠Release of Ca2 + via IP3R activates NCX to cause automaticity. ⺠T-tubule system is enriched in PV cardiomyocytes, in contrast to atrial cells.
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Authors
Yosuke Okamoto, Makoto Takano, Takayoshi Ohba, Kyoichi Ono,