Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2190874 | Journal of Molecular and Cellular Cardiology | 2011 | 8 Pages |
Abstract
⺠AC6 expression reduces of hypertrophy, increased cell survival, and improved calcium handling - effects that appear to be cAMP-independent. ⺠Unlike endogenous transgene AC6 is widely distributed in the cell, enabling interactions with previously inaccessible proteins. ⺠The beneficial effects of increased AC6 on cardiac function may reflect its interactions with kinases, phosphatases, and transcription factors.
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Authors
Mei Hua Gao, H. Kirk Hammond,