Article ID Journal Published Year Pages File Type
2190874 Journal of Molecular and Cellular Cardiology 2011 8 Pages PDF
Abstract
► AC6 expression reduces of hypertrophy, increased cell survival, and improved calcium handling - effects that appear to be cAMP-independent. ► Unlike endogenous transgene AC6 is widely distributed in the cell, enabling interactions with previously inaccessible proteins. ► The beneficial effects of increased AC6 on cardiac function may reflect its interactions with kinases, phosphatases, and transcription factors.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Authors
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