Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2196599 | Molecular and Cellular Endocrinology | 2011 | 5 Pages |
Abstract
Ghrelin is a peptide hormone that was originally isolated from the stomach as the endogenous ligand for the growth hormone secretagogue receptor (GHSR). Ghrelin has many functions, including the regulation of appetite and gut motility, growth hormone release from the anterior pituitary and roles in the cardiovascular and immune systems. Ghrelin and its receptor are expressed in a number of cancers and cancer cell lines and may play a role in processes associated with cancer progression, including cell proliferation, apoptosis, and cell invasion and migration.
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Authors
Lisa Chopin, Carina Walpole, Inge Seim, Peter Cunningham, Rachael Murray, Eliza Whiteside, Peter Josh, Adrian Herington,