Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2200746 | Neurochemistry International | 2012 | 9 Pages |
Abstract
⺠Glutamate facilitates Mn-induced apoptosis in neuronally differentiated P19 cells. ⺠Apoptotic signals ROS, caspase 3 and JNK increase when the two agents are combined. ⺠The anti-glutamatergic drug, riluzole, inhibits the apoptotic signals and cell death.
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Authors
Jerome A. Roth, Swetha Sridhar, Steven T. Singleton,